Adverse drug reactions (ADR)
Adverse drug reactions (ADR)
Adverse drug reactions (ADR)
Any noxious change which
– is suspected to be due to a drug,
– occurs at doses normally used in human,
– requires treatment or decrease in dose or
– indicates caution in the future use of same drug
Adverse drug event (ADE)
‘Any untoward medical occurrence that may present during treatment with a medicine,
But which does not necessarily have a causal relationship with the treatment.’
All drugs are capable of producing adverse effects and whenever a drug is given a risk is taken
Severity of Adverse drug reactions
1.Minor
2.Moderate
3.Severe
4.Lethal
Pharmacovigilance
‘Science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug related problems.’
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