Allergy & Hypersensitivity Reactions
Allergy & Hypersensitivity Reactions
Allergy: Allergy is Hypersensitivity caused by exposure to a particular antigen (allergen) resulting in a marked increase in reactivity to that antigen on subsequent exposure, sometimes resulting in harmful immunologic consequences.
Allergy: Allergy is An acquired hypersensitivity to certain drugs and biologic materials.
Four Types of Hypersensitivity:
1.Type I Hypersensitivity: Immediate; in allergy, atopy, and anaphylaxis
2.Type II Hypersensitivity: Ab-dependent Cytotoxicity
3.Type III Hypersensitivity: Immune Complex Disease
4.Type IV Hypersensitivity: delayed type/cell-mediated immune responses
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Type I Hypersensitivity
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Local
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Systemic
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Asthma
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Anaphylaxis
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Hay Fever
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Cassion’s Disease
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Atopy
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Casoni’s Test
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Type II Hypersensitivity
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Phagocytic
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Inflammatory
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Antibody Mediated Cellular Dysfunction
(Previously Known As Type 5 Hyper Sensitivity)
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Warm AIHA
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Good Pasteur Syndrome
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Graves Disease
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ABO Incompatibility
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Acute Rheumatic Fever
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Myasthenia Gravis
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Rh Incompatibility
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Pernicious Anaemia
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ITP
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HDN
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Type III Hypersensitivity
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Localised
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Systemic
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Arthus Reaction
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SLE
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Farmer’s Lung
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Reactive Arthritis
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Hypersensitivity Pneumonitis
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H S Purpura
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Polyarteritis Nodosa (PAN)
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Serum Sickness
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Type II Lepra Reaction
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Type IV Hypersensitivity
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Immune
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Non-Immune
Or Reactionary
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Infective
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Noninfective
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Suture
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MTB/ Tuberculin Skin Test
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Wegners Granulomatosis
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Talc
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Leprosy/ Lepromin Test
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Crohn’s Disease
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Syphilis
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Sarcoidosis
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Cat Scratch
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Histoplasmosis
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Coccioidomycosis
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