Allergy & Hypersensitivity Reactions

Allergy & Hypersensitivity Reactions

Allergy: Allergy is Hypersensitivity caused by exposure to a particular antigen (allergen) resulting in a marked increase in reactivity to that antigen on subsequent exposure, sometimes resulting in harmful immunologic consequences.
Allergy: Allergy is An acquired hypersensitivity to certain drugs and biologic materials.
allergy


Four Types of Hypersensitivity:
1.Type I Hypersensitivity: Immediate; in allergy, atopy, and anaphylaxis

2.Type II Hypersensitivity: Ab-dependent Cytotoxicity

3.Type III Hypersensitivity: Immune Complex Disease

4.Type IV Hypersensitivity: delayed type/cell-mediated immune responses

Type I Hypersensitivity
Local
Systemic
Asthma
Anaphylaxis
Hay Fever
Cassion’s Disease
Atopy
Casoni’s Test

Type II Hypersensitivity
Phagocytic
Inflammatory
Antibody Mediated Cellular Dysfunction
(Previously Known As Type 5 Hyper Sensitivity)
Warm AIHA
Good Pasteur Syndrome
Graves Disease
ABO Incompatibility
Acute Rheumatic Fever
Myasthenia Gravis
Rh Incompatibility
Pernicious Anaemia
ITP
HDN

Type III Hypersensitivity
Localised
Systemic
Arthus Reaction
SLE
Farmer’s Lung
Reactive Arthritis
Hypersensitivity Pneumonitis
H S Purpura
Polyarteritis Nodosa (PAN)
Serum Sickness
Type II Lepra Reaction

Type IV Hypersensitivity
Immune
Non-Immune
Or Reactionary
Infective
Noninfective
Suture
MTB/ Tuberculin Skin Test
Wegners Granulomatosis
Talc
Leprosy/ Lepromin Test
Crohn’s Disease
Syphilis
Sarcoidosis
Cat Scratch
Histoplasmosis
Coccioidomycosis


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