Translocation Between Chromosomes
Translocation Between Chromosomes
The designation t (A; B)(p1;q2) is used to denote a translocation between chromosome A and B.
The information in the second set of parentheses gives the precise location within the chromosome for chromosomes A and B respectively-
With p indicating the short arm, q indicating the long arm,
And the number after p or q refers to regions, bands, and sub-bands seen when staining the chromosome with a staining dye.
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Translocation
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Associated diseases
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t(8;14) (q24;q32)
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Burkitt’s lymphoma
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t(11;14) (q13;q32)
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Mantle cell lymphoma
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t(14;18) (q32;q21)
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Follicular lymphoma
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t(11;18) (q21;q21)
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MALT lymphoma
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t(10;(various)) (q11;q(various))
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Papillary thyroid cancer
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t(2;3) (q13;q25)
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Follicular thyroid cancer
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t(8;21) (q22;q22)
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Acute myeloblastic leukemia
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t(9;22)(q34;q11)
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CML, AML
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t(15;17)
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Acute promyelocytic leukemia
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t(12;15)(p13;q25)
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AML
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t(9;12)(p24;p13)
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CML, ALL
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t(12;21)(p12;q22)
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ALL
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t(2;5) (p23;q35)
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Anaplastic large cell lymphoma
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t(11;22) (q24;q11.2-12)
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Ewing’s sarcoma
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t(1;12) (q21;q13)
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Acute myelogenous leukemia
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t(X;18) (p11.2;q11.2)
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Synoval sarcoma
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