Translocation Between Chromosomes

Translocation Between Chromosomes

The designation t (A; B)(p1;q2) is used to denote a translocation between chromosome A and B.

The information in the second set of parentheses gives the precise location within the chromosome for chromosomes A and B respectively-

With p indicating the short arm, q indicating the long arm,

And the number after p or q refers to regions, bands, and sub-bands seen when staining the chromosome with a staining dye.


Translocation
Associated diseases
t(8;14) (q24;q32)
Burkitt’s lymphoma
t(11;14) (q13;q32)
Mantle cell lymphoma
t(14;18) (q32;q21)
Follicular lymphoma
t(11;18) (q21;q21)
MALT lymphoma
t(10;(various)) (q11;q(various))
Papillary thyroid cancer
t(2;3) (q13;q25)
Follicular thyroid cancer
t(8;21) (q22;q22)
Acute myeloblastic leukemia
t(9;22)(q34;q11)
CML, AML
t(15;17)
Acute promyelocytic leukemia
t(12;15)(p13;q25)
AML
t(9;12)(p24;p13)
CML, ALL
t(12;21)(p12;q22)
ALL
t(2;5) (p23;q35)
Anaplastic large cell lymphoma
t(11;22) (q24;q11.2-12)
Ewing’s sarcoma
t(1;12) (q21;q13)
Acute myelogenous leukemia
t(X;18) (p11.2;q11.2)
Synoval sarcoma



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