Category: CLINICAL

Hypersensitivity Reactions

Hypersensitivity reactions Four Types of Hypersensitivity: 1.Type I Hypersensitivity: Immediate; in allergy, atopy, and anaphylaxis 2.Type II Hypersensitivity: Ab-dependent Cytotoxicity 3.Type III Hypersensitivity: Immune Complex Disease 4.Type IV Hypersensitivity: delayed type/cell-mediated immune responses Type I Hypersensitivity Type II Hypersensitivity Type III Hypersensitivity Type IV Hypersensitivity Local Systemic Phagocytic Inflammatory Antibody Mediated Cellular Dysfunction (Previously Known

Abnormal Gait

Abnormal Gait Posture Of The Patient During Walking Gait Attitude Of The Patient On Standing Stance Posture Of The Patient In Bed Decubitus Different Types Of Gait Neurogenic: 1.Hemiplegic / Spastic Gait – Hemiplegic Patient (UMN Lesion ) After Recovery 2.Scissors / Spastic Paraplegic Gait  [Patient Stands With Crossed Legs (Often With A Stick In

Tremor

Tremor Involuntary, Repetitive, Oscillatory Movements Of A Part Of The Body Around A Fixed Point. Classification: According To Relationship With Posture 1.Static Tremor  Tremor At Rest  Coarse In Nature Seen In Parkinsonism 2.Kinetic/ Postural/ Action Tremor  Fine In Nature  The Patient Is Asked To Outstretch His Hands With Separated Fingers For The Appearance Of Tremor

Trophic Changes

Trophic Changes 1.Trophic Changes In The Skin & Appendages: Dry/ Rough/ Cold Skin Pigmentation Local Cyanosis/Local Oedema Hypohydrosis (Lack Of Sweating) Hypotrichosis(Fall Of Hairs) Brittle Nails 2.Trophic Ulcers: Trophic Ulcer- Usually Present Over The Heel Or Ball Of The Great Toe Sites Examined- On The Lateral Malleolus Back Of The Heel Of Foot Shoulder Girdles

Fatigue

Fatigue It is the excessive tiredness on exertion.The severe form of fatigue is known as ‘exhaustion’. Common Causes 1.Physiological– overwork, insomnia. 2.Pathological– Nutritional Deficiency, Dyselectrolytaemia Congestive cardiac failure (CCF), Hepatic Failure, Uraemia, Malignancy, Immunocompromised States, Sleep-Apnoea Syndrome Myxoedema, Diabetes Mellitus, Addison’s Disease, Thyrotoxicosis Tuberculosis, Brucellosis, Post-Viral Infectious States (e.g. Influenza Or Infectious Mononucleosis), Collagen Vascular

Physical Examination of the Abdomen

Physical Examination of the Abdomen Examiner & Patient Position Examiner Patient On the right side of the Patient 1. Lying on Flat bed.2. Arms on the sides3. Abdomen exposed4. Legs extended during inspection5. Legs bent Quadrants of Abdomen Right upper quadrant Left upper quadrant Right lower quadrant Left lower quadrant Regions of Abdomen Epigastric Umbilical

Clinical Examination of Cardiovascular System

Cardiovascular System Cardinal Symptoms 1. Breathlessness 2. Dyspnoea – Dyspnoea Is An Abnormal Awareness Of Breathing Occurring Either At Rest Or An Unexpectedly Low Level Of Exertion. Orthopnoea – In Patient With Heart Failure Lying Flat Causes A Steep Rise In Left Atrial Pressure, Resulting In Pulmonary Congestion And Severe Dyspnoea. PND – Frank Pulmonary